Researchers here have found a way to avoid the toxicity of some plant-derived cancer-killing drugs by 'masking' their toxicity until they reach their targets, potentially leading to more effective cancer therapies.
Revelation of oligomer dynamics provides hope for new Alzheimer's therapies
Revealing for the first time the surprising behaviour of toxic oligomers in the amyloid aggregation process involved in Alzheimer’s and other protein misfolding diseases, thus opening up routes for new therapies against these dreaded killers.
Heartfelt tributes are being paid to our distinguished colleague Professor Sir Christopher Dobson - a pioneering researcher in the field of neurodegenerative diseases - who died on 8 September 2019, aged 69.
Artwork 'Matter in Grey' illustrates progression of Alzheimer's
The artwork created by artist Jacob van der Beugel for the façade of the building illustrates the progression of Alzheimer's and is featured in Trail 1 of the Cambridge Sculpture Trails.
Wren Therapeutics, based in the Chemistry of Health Incubator, has received significant funding to help it develop its unique approach to investigating protein misfolding diseases such as Alzheimer's and Parkinson's.
Researchers identify a tau homeostasis signature that underlies Alzheimer’s disease
Researchers have long known that Alzheimer’s is characterized by abnormal clusters of rogue misfolded proteins. A healthy brain has a “quality control system” that effectively keeps them at bay. But problems start when this system goes wrong.
"Our scientists, and this building, offer hope," said Vice-Chancellor Stephen J Toope as he officially opened the Chemistry of Health building in September 2018.
June 2018: researchers have started moving into the Chemistry of Health building, a brand new facility promoting the translation of fundamental research into clinical and commercial applications.